@article{MaiHunGaw22,
author = {Maini, Philip K.
and Hunter, Peter J.
and Gawthrop, Peter J.
and Smith, Nic P.},
title = {{Edmund John Crampin} 1973--2021},
journal = {Bulletin of Mathematical Biology},
year = 2022,
month = {Jan},
day = 29,
volume = 84,
number = 3,
pages = 35,
issn = {1522-9602},
doi = {10.1007/s11538-021-00987-0}
}
@article{GawPan22,
title = {Network thermodynamics of biological systems: A bond graph approach},
journal = {Mathematical Biosciences},
volume = 352,
pages = 108899,
year = 2022,
issn = {0025-5564},
doi = {https://doi.org/10.1016/j.mbs.2022.108899},
author = {Peter J. Gawthrop and Michael Pan},
keywords = {Systems biology, Bond graph, Energy-based, Photosynthesis, Electrochemical transduction},
abstract = {Edmund Crampin (1973-2021) was at the forefront of Systems Biology research and his work will influence the field for years to come. This paper brings together and summarises the seminal work of his group in applying energy-based bond graph methods to biological systems. In particular, this paper: (a) motivates the need to consider energy in modelling biology; (b) introduces bond graphs as a methodology for achieving this; (c) describes extensions to modelling electrochemical transduction; (d) outlines how bond graph models can be constructed in a modular manner and (e) describes stoichiometric approaches to deriving fundamental properties of reaction networks. These concepts are illustrated using a new bond graph model of photosynthesis in chloroplasts.}
}
@article{LorGolKamGaw22,
author = {Loram, Ian and Gollee, Henrik and Kamp, Cornelis van de and Gawthrop, Peter},
journal = {IEEE Transactions on Biomedical Engineering},
title = {Is intermittent control the source of the non-linear oscillatory component (0.2-2{Hz}) in human balance control?},
year = 2022,
pages = {1-1},
doi = {10.1109/TBME.2022.3174927}
}
@article{GawPan22a,
author = {Gawthrop, Peter J. and Pan, Michael },
title = {Energy-based advection modelling using bond graphs},
journal = {Journal of The Royal Society Interface},
volume = 19,
number = 195,
pages = 20220492,
year = 2022,
doi = {10.1098/rsif.2022.0492},
abstract = { Advection, the transport of a substance by the flow of a fluid, is a key process in biological systems. The energy-based bond graph approach to modelling chemical transformation within reaction networks is extended to include transport and thus advection. The approach is illustrated using a simple model of advection via circulating flow and by a simple pharmacokinetic model of anaesthetic gas uptake. This extension provides a physically consistent framework for linking advective flows with the fluxes associated with chemical reactions within the context of physiological systems in general and the human physiome in particular. }
}
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